Note 4 at Acts 14:6: Lystra was a small city in Lycaonia (see note 6 at this verse), a Roman colony of Asia Minor. On this first visit to Lystra by Paul, the Lord healed a man who had been cripple from birth (Acts 14:8-10). The people of the city would have done sacrifice to Paul and Barnabas if they had not restrained them (Acts 14:11-18). These same people who wanted to worship the apostles, later stoned them and left them for dead (Acts 14:19-20).

It was either at Lystra or Derbe that Paul met Timothy on his second missionary journey (Acts 16:1-2). Paul passed through this area on all three of his missionary trips. Lystra was approximately 20 miles south-southwest of Iconium (see note 3 at Acts 13:51, p. ???) and 25 miles north west of Derbe (see note 5 at this verse).

Note 5 at Acts 14:6: Derbe was a city in the southeastern part of the Roman province of Lycaonia (see note 6 at this verse) located in Asia Minor. The exact location of Derbe has recently been disputed since an inscription was found about thirty miles east of what was commonly thought to be the city's site. Therefore, Derbe was either twenty or fifty miles distant from Lystra.

Paul went through Derbe on all three of his missionary trips. The book of Galatians was written to the believers in Iconium, Lystra and Derbe. It was either at Derbe or Lystra that Paul first met Timothy (Acts 16:1-2). Gaius, who became a companion of Paul was from Derbe (Acts 20:4).

Note 6 at Acts 14:6: Lycaonia was a small Roman province of Asia Minor bordered on the north by Galatia, the east by Cappadocia (see note 9 at Acts 2:9, p. 578), on the south by Cilicia (see note 5 at Acts 6:9, p. 602), and Pisidia on the west. It's principal towns were Iconium (see note 3 at Acts 13:51, p. 653), Lystra (see note 4 at this verse), and Derbe (see note 5 at this verse).

The people of this region spoke a peculiar dialect which was a corrupted Greek mingled with Syriac. This is what Acts 14:11 refers to when it mentions the speech of Lycaonia.