Note 1 at Acts 16:6: Galatia was a province in central Asia Minor. Paul and Barnabas had ministered in Iconium, Lystra, and Derbe, cities of Galatia on their first missionary journey. The epistle to the Galatians was written to the believers in this area.

Note 2 at Acts 16:6: There is no explanation given as to why the Holy Ghost forbid Paul and his company to preach the Word in these areas. It is certain that it was not because the Lord didn't love these people and desire their salvation. Judging from the vision that Paul had of the man in Macedonia calling for help (v. 9), it can be supposed that the people of Macedonia were simply hungrier for the gospel.

Note 3 at Acts 16:6: In Paul's time, Asia designated the area that would correspond to western portions of present day Turkey. This was the land bounded by the Mediterranean Sea and the Black Sea and west of Galatia (see note 1 at this verse). Mysia and Bithynia were northwestern and northern portions of Asia. The seven churches that the book of Revelation was written to were in Asia (Rev. 1:11).